Molecule Details
InChIKeyVIZWJTHWUUQVGO-UHFFFAOYSA-N
Compound Name6-chloro-N-prop-2-enyl-4-(1H-pyrrolo[2,3-b]pyridin-3-yl)pyridin-2-amine
Canonical SMILESC=CCNc1cc(-c2c[nH]c3ncccc23)cc(Cl)n1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)9
Pfam Stratification Cross-Family
Avg pChEMBL7.27
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (9)
Target Gene Organism Category Pfam pChEMBL Type Source
O00311 CDC7 Homo sapiens Human PF00069 9.1 Ki ChEMBL
Q9HAZ1 CLK4 Homo sapiens Human PF00069 8.4 Ki ChEMBL
O75116 ROCK2 Homo sapiens Human PF25346 PF00069 PF08912 7.9 Ki ChEMBL
Q9H2X6 HIPK2 Homo sapiens Human PF00069 7.3 Ki ChEMBL
P24941 CDK2 Homo sapiens Human PF00069 7.0 Ki ChEMBL
P49841 GSK3B Homo sapiens Human PF00069 7.0 Ki ChEMBL
P17612 PRKACA Homo sapiens Human PF00069 6.4 Ki ChEMBL
Q9NWZ3 IRAK4 Homo sapiens Human PF07714 6.2 Ki ChEMBL
P11309 PIM1 Homo sapiens Human PF00069 6.1 Ki ChEMBL