Molecule Details
InChIKeyVIPSEWNPWLYICF-UHFFFAOYSA-N
Compound Name1-Ethyl-3-[3-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]phenyl]urea
Canonical SMILESCCNC(=O)Nc1cccc(CCN2CCN(c3cccc4nc(C)ccc34)CC2)c1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)10
Pfam Stratification Cross-Family
Avg pChEMBL7.34
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (10)
Target Gene Organism Category Pfam pChEMBL Type Source
P28221 HTR1D Homo sapiens Human PF00001 9.8 Ki ChEMBL
P28222 HTR1B Homo sapiens Human PF00001 8.9 Ki ChEMBL
P08908 HTR1A Homo sapiens Human PF00001 8.7 Ki ChEMBL
P34969 HTR7 Homo sapiens Human PF00001 7.4 Ki ChEMBL
P35462 DRD3 Homo sapiens Human PF00001 6.9 Ki ChEMBL
P14416 DRD2 Homo sapiens Human PF00001 6.5 Ki ChEMBL
P28223 HTR2A Homo sapiens Human PF00001 6.5 Ki ChEMBL
P41595 HTR2B Homo sapiens Human PF00001 6.4 Ki ChEMBL
Q12809 KCNH2 Homo sapiens Human PF00027 PF00520 PF13426 6.2 Ki ChEMBL;BindingDB
P28335 HTR2C Homo sapiens Human PF00001 6.1 Ki ChEMBL