4,4'-{3-[(4-Hydroxyphenyl)amino]-1h-Pyrazole-4,5-Diyl}diphenol

InChIKey	`VIJBEUTVNBPGIU-UHFFFAOYSA-N`
Compound Name	4,4'-{3-[(4-Hydroxyphenyl)amino]-1h-Pyrazole-4,5-Diyl}diphenol
Canonical SMILES	`Oc1ccc(Nc2[nH]nc(-c3ccc(O)cc3)c2-c2ccc(O)cc2)cc1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	19
Pfam Stratification	Cross-Family
Avg pChEMBL	6.49
Source	ChEMBL

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P51812	RPS6KA3	Homo sapiens	Human	PF00069 PF00433	7.8	Ki	ChEMBL
O75116	ROCK2	Homo sapiens	Human	PF25346 PF00069 PF08912	7.3	Ki	ChEMBL
Q9HBY8	SGK2	Homo sapiens	Human	PF00069 PF00433	7.0	Ki	ChEMBL
Q9UEE5	STK17A	Homo sapiens	Human	PF00069	6.9	Ki	ChEMBL
Q9Y4K4	MAP4K5	Homo sapiens	Human	PF00780 PF00069	6.7	Ki	ChEMBL
O95819	MAP4K4	Homo sapiens	Human	PF00780 PF00069	6.6	Ki	ChEMBL
P17948	FLT1	Homo sapiens	Human	PF07679 PF00047 PF13927 PF22971 PF07714 PF21339 PF17988 PF22854	6.6	Ki	ChEMBL
O43293	DAPK3	Homo sapiens	Human	PF00069	6.5	Ki	ChEMBL
P07949	RET	Homo sapiens	Human	PF00028 PF07714 PF17756 PF17812 PF17813 PF22540	6.5	Ki	ChEMBL
P36888	FLT3	Homo sapiens	Human	PF00047 PF07714	6.4	Ki	ChEMBL
P04629	NTRK1	Homo sapiens	Human	PF13855 PF16920 PF07714 PF18613	6.3	Ki	ChEMBL
Q13464	ROCK1	Homo sapiens	Human	PF25346 PF00069 PF08912	6.3	Ki	ChEMBL
P23443	RPS6KB1	Homo sapiens	Human	PF00069 PF00433	6.2	Ki	ChEMBL
Q13976	PRKG1	Homo sapiens	Human	PF00027 PF16808 PF00069	6.2	Ki	ChEMBL
P11362	FGFR1	Homo sapiens	Human	PF07679 PF00047 PF07714	6.1	Ki	ChEMBL
O00418	EEF2K	Homo sapiens	Human	PF02816	6.0	Ki	ChEMBL
O43781	DYRK3	Homo sapiens	Human	PF00069	6.0	Ki	ChEMBL
Q14680	MELK	Homo sapiens	Human	PF02149 PF00069 PF21594	6.0	Ki	ChEMBL
Q16288	NTRK3	Homo sapiens	Human	PF07679 PF00047 PF13855 PF16920 PF01462 PF07714	6.0	Ki	ChEMBL