Molecule Details
| InChIKey | VHZPUDNSVGRVMB-RXDLHWJPSA-N |
|---|---|
| Compound Name | Lonaprisan |
| Canonical SMILES | CC(=O)c1ccc([C@H]2C[C@@]3(C)[C@@H](CC[C@@]3(O)C(F)(F)C(F)(F)F)[C@@H]3CCC4=CC(=O)CCC4=C32)cc1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 2 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 9.39 |
| Source | BindingDB;ChEMBL |
2D Structure
Activity Profile
DrugBank Annotations
| DrugBank ID | DB16221 |
|---|---|
| Drug Name | Lonaprisan |
| CAS Number | 211254-73-8 |
| Groups | investigational |
| ATC Codes | nan |
| Description | Lonaprisan is under investigation in clinical trial NCT00555919 (ZK 230211 in Postmenopausal Woman With Metastatic Breast Cancer). |
Categories: Estranes Fused-Ring Compounds Hydrocarbons, Fluorinated Hydrocarbons, Halogenated Steroids
Cross-references: BindingDB: 50409115 CHEMBL146032 ChemSpider: 5293745 Wikipedia: Lonaprisan