Molecule Details
| InChIKey | VHPRRJZGFMSHQV-JUCHKJSUSA-N |
|---|---|
| Compound Name | 5'-([(3S)-3-amino-3-carboxypropyl]{[1-(3,3-diphenylpropyl)azetidin-3-yl]methyl}amino)-5'-deoxyadenosine |
| Canonical SMILES | Nc1ncnc2c1ncn2[C@@H]1O[C@H](CN(CC[C@H](N)C(=O)O)CC2CN(CCC(c3ccccc3)c3ccccc3)C2)[C@@H](O)[C@H]1O |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 5 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 6.86 |
| Source | ChEMBL |
2D Structure
Activity Profile
Target Activities (5)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P61964 | WDR5 | Homo sapiens | Human | PF25175 | 6.9 | IC50 | ChEMBL |
| Q03164 | KMT2A | Homo sapiens | Human | PF05965 PF05964 PF00628 PF00856 PF02008 PF13771 | 6.9 | IC50 | ChEMBL |
| Q15291 | RBBP5 | Homo sapiens | Human | PF00400 | 6.9 | IC50 | ChEMBL |
| Q9C005 | DPY30 | Homo sapiens | Human | PF05186 | 6.9 | IC50 | ChEMBL |
| Q9UBL3 | ASH2L | Homo sapiens | Human | PF21198 PF21257 PF00622 | 6.9 | IC50 | ChEMBL |