Molecule Details
InChIKeyVHOZWHQPEJGPCC-AZXNYEMZSA-N
Compound NamePri-724
Canonical SMILESC[C@H]1[C@H]2N(C(=O)CN(C)N2C(=O)NCc2ccccc2)[C@@H](Cc2ccc(OP(=O)(O)O)cc2)C(=O)N1Cc1cccc2cccnc12
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)3
Pfam Stratification Cross-Family
Avg pChEMBL6.82
SourceChEMBL
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB15034
Drug NameFoscenvivint
CAS Number1198780-38-9
Groups investigational
ATC Codes nan
DescriptionPRI-724 is under investigation in clinical trial NCT03620474 (Safety and Effectiveness of PRI-724 for Hepatitis C or B Virus Derived Liver Cirrhosis).

Categories: Pyrimidines
Cross-references: ChemSpider: 64854018
Target Activities (3)
Target Gene Organism Category Pfam pChEMBL Type Source
P15884 TCF4 Homo sapiens Human PF00010 6.8 IC50 ChEMBL
P35222 CTNNB1 Homo sapiens Human PF00514 6.8 IC50 ChEMBL
Q92793 CREBBP Homo sapiens Human PF00439 PF09030 PF08214 PF02172 PF23570 PF06001 PF02135 PF00569 6.8 IC50 ChEMBL
DrugBank Target Actions (1)
Target Gene Target Name Action Type
Q92793 CREBBP CREB-binding protein modulator targets