Molecule Details
| InChIKey | VGRBFVDNFGSMNW-UHFFFAOYSA-N |
|---|---|
| Compound Name | N-[2-methoxy-4-(1H-pyrazol-4-yl)phenyl]-2,3-dihydro-1,4-benzodioxine-2-carboxamide |
| Canonical SMILES | COc1cc(-c2cn[nH]c2)ccc1NC(=O)C1COc2ccccc2O1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 3 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 6.98 |
| Source | BindingDB;ChEMBL |
2D Structure
Activity Profile
Target Activities (3)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| O75116 | ROCK2 | Homo sapiens | Human | PF25346 PF00069 PF08912 | 8.5 | IC50 | ChEMBL;BindingDB |
| Q5VT25 | CDC42BPA | Homo sapiens | Human | PF00130 PF00780 PF08826 PF15796 PF25346 PF00069 PF00433 | 6.4 | IC50 | BindingDB |
| P17612 | PRKACA | Homo sapiens | Human | PF00069 | 6.0 | IC50 | BindingDB |