N-(1-(cyclopropylsulfonyl)piperidin-4-yl)-4-(difluoromethyl)-1-isopropyl-1H-[1,2,3]triazolo[4,5-h]quinazolin-8-amine

InChIKey	`VGQBMNJRVGPBKT-UHFFFAOYSA-N`
Compound Name	N-(1-(cyclopropylsulfonyl)piperidin-4-yl)-4-(difluoromethyl)-1-isopropyl-1H-[1,2,3]triazolo[4,5-h]quinazolin-8-amine
Canonical SMILES	`CC(C)n1nnc2c(C(F)F)cc3cnc(NC4CCN(S(=O)(=O)C5CC5)CC4)nc3c21`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Homologous
Avg pChEMBL	9.07
Source	BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P24941	CDK2	Homo sapiens	Human	PF00069	9.7	IC50	BindingDB
P11802	CDK4	Homo sapiens	Human	PF00069	9.0	IC50	BindingDB
Q00534	CDK6	Homo sapiens	Human	PF00069	8.5	IC50	BindingDB