Molecule Details
InChIKeyVGBVAARMQYYITG-DESRROFGSA-N
Compound NameTridecactide
Canonical SMILESCSCC[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](N)CO)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@H](C(=O)O)C(C)C
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)3
Pfam Stratification Homologous
Avg pChEMBL8.56
SourceBindingDB
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB15687
Drug NameTridecactide
CAS Number22006-64-0
Groups investigational
ATC Codes nan
DescriptionTridecactide, also known as alpha-corticotropin 1-13, is a deacetylated and deaminated alpha-melanocyte stimulating hormone, which may have antipyretic, anti-inflammatory, and antimicrobial effects.[A203210] Tridecactide, along with [metenkefalin], are under investigation as an immunomodulatory ther...

Categories: Experimental Unapproved Treatments for COVID-19 Melanocyte-Stimulating Hormones
Cross-references: ChemSpider: 17287850
Target Activities (3)
Target Gene Organism Category Pfam pChEMBL Type Source
Q01726 MC1R Homo sapiens Human PF00001 10.4 Ki BindingDB
P41968 MC3R Homo sapiens Human PF00001 8.4 Ki BindingDB
P32245 MC4R Homo sapiens Human PF00001 6.9 Ki BindingDB