Molecule Details
InChIKeyVFNJLPYDAYDGKC-XUTJKUGGSA-N
Canonical SMILESCOc1nc(Nc2ncc3c4ccncc4n([C@H]4CC[C@H](C)CC4)c3n2)ccc1N1CCC(N(C)C)CC1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)5
Pfam Stratification Cross-Family
Avg pChEMBL7.79
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (5)
Target Gene Organism Category Pfam pChEMBL Type Source
P36888 FLT3 Homo sapiens Human PF00047 PF07714 9.7 IC50 ChEMBL;BindingDB
P11802 CDK4 Homo sapiens Human PF00069 8.5 IC50 ChEMBL;BindingDB
P24385 CCND1 Homo sapiens Human PF02984 PF00134 8.5 IC50 ChEMBL
P06493 CDK1 Homo sapiens Human PF00069 6.1 IC50 ChEMBL;BindingDB
P14635 CCNB1 Homo sapiens Human PF02984 PF00134 6.1 IC50 ChEMBL