Molecule Details
| InChIKey | VFLPOFHPMNYCOH-JMIUGGIZSA-N |
|---|---|
| Compound Name | (2Z)-6-[(2,6-dichlorophenyl)sulfonylmethyl]-2-[(4-hydroxy-3-nitrophenyl)methylidene]-4H-1,4-benzothiazin-3-one |
| Canonical SMILES | O=C1Nc2cc(CS(=O)(=O)c3c(Cl)cccc3Cl)ccc2S/C1=C\c1ccc(O)c([N+](=O)[O-])c1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 7 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 7.71 |
| Source | ChEMBL |
2D Structure
Activity Profile
Target Activities (7)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q9UKE5 | TNIK | Homo sapiens | Human | PF00780 PF00069 | 8.3 | IC50 | ChEMBL |
| Q9Y463 | DYRK1B | Homo sapiens | Human | PF00069 | 8.2 | IC50 | ChEMBL |
| P19784 | CSNK2A2 | Homo sapiens | Human | PF00069 | 7.8 | IC50 | ChEMBL |
| Q13627 | DYRK1A | Homo sapiens | Human | PF00069 | 7.8 | IC50 | ChEMBL |
| P67870 | CSNK2B | Homo sapiens | Human | PF01214 | 7.3 | IC50 | ChEMBL |
| P68400 | CSNK2A1 | Homo sapiens | Human | PF00069 | 7.3 | IC50 | ChEMBL |
| Q8NEV1 | CSNK2A3 | Homo sapiens | Human | PF00069 | 7.3 | IC50 | ChEMBL |