Molecule Details
| InChIKey | VEZQCXWMPWTPJL-UHFFFAOYSA-N |
|---|---|
| Compound Name | 1-(6-(Dihydro-1H-furo[3,4-c]pyrrol-5(3H,6H,6aH)-yl)quinolin-4-yl)-3-(pyrazin-2-yl)urea |
| Canonical SMILES | O=C(Nc1cnccn1)Nc1ccnc2ccc(N3CC4COCC4C3)cc12 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 5 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.24 |
| Source | ChEMBL |
2D Structure
Activity Profile
Target Activities (5)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P49841 | GSK3B | Homo sapiens | Human | PF00069 | 8.1 | Ki | ChEMBL |
| P49840 | GSK3A | Homo sapiens | Human | PF00069 | 8.0 | Ki | ChEMBL |
| P49336 | CDK8 | Homo sapiens | Human | PF00069 | 7.0 | Ki | ChEMBL |
| Q9HAZ1 | CLK4 | Homo sapiens | Human | PF00069 | 7.0 | Ki | ChEMBL |
| Q9Y463 | DYRK1B | Homo sapiens | Human | PF00069 | 6.1 | Ki | ChEMBL |