VEZBREXQDQRJTD-KBPBESRZSA-N

InChIKey	`VEZBREXQDQRJTD-KBPBESRZSA-N`
Canonical SMILES	`COc1cc2c(Nc3ccc(Br)c(Cl)c3F)ncnc2cc1OC[C@@H]1CN2CCC[C@H]2CO1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	2
Pfam Stratification	Homologous
Avg pChEMBL	6.79
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P04626	ERBB2	Homo sapiens	Human	PF00757 PF14843 PF07714 PF01030 PF21314	7.3	IC50	ChEMBL
P54760	EPHB4	Homo sapiens	Human	PF14575 PF25599 PF01404 PF07699 PF00041 PF07714 PF00536	6.3	IC50	ChEMBL;BindingDB