H-Pra-Tyr-Cys(1)-Gln-Lys-Trp-Nle-Trp-Thr-Cys(2)-Asp-Ser-Lys-Arg-Ala-Cys(3)-Cys(1)-Glu-Gly-Leu-Arg-Cys(2)-Lys-Leu-Trp(5-Br)-Cys(3)-Arg-Lys-Glu-Ile-NH2

InChIKey	`VEEQSZWXUOUXPZ-ZEGFWLDJSA-N`
Compound Name	H-Pra-Tyr-Cys(1)-Gln-Lys-Trp-Nle-Trp-Thr-Cys(2)-Asp-Ser-Lys-Arg-Ala-Cys(3)-Cys(1)-Glu-Gly-Leu-Arg-Cys(2)-Lys-Leu-Trp(5-Br)-Cys(3)-Arg-Lys-Glu-Ile-NH2
Canonical SMILES	C#CC[C@H](N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H]1CSSC[C@@H]2NC(=O)[C@@H]3CSSC[C@@H](C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@H](C(N)=O)[C@@H](C)CC)NC(=O)[C@H](Cc4c[nH]c5ccc(Br)cc45)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc4c[nH]c5ccccc45)NC(=O)[C@H](CCCC)NC(=O)[C@H](Cc4c[nH]c5ccccc45)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(N)=O)NC1=O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](C)C(=O)N3)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC2=O
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	5
Pfam Stratification	Homologous
Avg pChEMBL	7.38
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
Q15858	SCN9A	Homo sapiens	Human	PF00520 PF24609 PF06512 PF11933	9.6	IC50	ChEMBL;BindingDB
P35499	SCN4A	Homo sapiens	Human	PF00520 PF24609 PF06512	7.3	IC50	ChEMBL;BindingDB
Q9UQD0	SCN8A	Homo sapiens	Human	PF00520 PF24609 PF06512 PF11933	7.2	IC50	ChEMBL;BindingDB
Q14524	SCN5A	Homo sapiens	Human	PF00520 PF24609 PF06512 PF11933	6.6	IC50	ChEMBL;BindingDB
Q9Y5Y9	SCN10A	Homo sapiens	Human	PF00520 PF24609 PF06512	6.3	IC50	ChEMBL;BindingDB