2-N-[4-(6,7-dihydro-5H-pyrrolo[2,1-c][1,2,4]triazol-3-yl)-2-methoxyphenyl]-8-N-(2,2-dimethylpropyl)-6-methylpyrido[3,4-d]pyrimidine-2,8-diamine

InChIKey	`VDYTVNXJBMDQBM-UHFFFAOYSA-N`
Compound Name	2-N-[4-(6,7-dihydro-5H-pyrrolo[2,1-c][1,2,4]triazol-3-yl)-2-methoxyphenyl]-8-N-(2,2-dimethylpropyl)-6-methylpyrido[3,4-d]pyrimidine-2,8-diamine
Canonical SMILES	`COc1cc(-c2nnc3n2CCC3)ccc1Nc1ncc2cc(C)nc(NCC(C)(C)C)c2n1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Cross-Family
Avg pChEMBL	7.07
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P33981	TTK	Homo sapiens	Human	PF00069	7.7	IC50	ChEMBL;BindingDB
P20248	CCNA2	Homo sapiens	Human	PF02984 PF00134 PF16500	6.7	IC50	ChEMBL
P24941	CDK2	Homo sapiens	Human	PF00069	6.7	IC50	ChEMBL;BindingDB