Molecule Details
| InChIKey | VDQWRDKJEXBYMS-UHFFFAOYSA-N |
|---|---|
| Compound Name | 4-Hydroxy-3-{[2-(4-isopropyl-phenyl)-ethyl]-methyl-sulfamoyl}-benzamidine |
| Canonical SMILES | CC(C)c1ccc(CCN(C)S(=O)(=O)c2cc(C(=N)N)ccc2O)cc1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 6.39 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P00742 | F10 | Homo sapiens | Human | PF00008 PF14670 PF00594 PF00089 | 7.2 | Ki | ChEMBL;BindingDB |
| P07477 | PRSS1 | Homo sapiens | Human | PF00089 | 6.1 | Ki | ChEMBL |
| P07478 | PRSS2 | Homo sapiens | Human | PF00089 | 6.1 | Ki | ChEMBL |
| P35030 | PRSS3 | Homo sapiens | Human | PF00089 | 6.1 | Ki | ChEMBL |