Molecule Details
InChIKeyVCPMZDWBEWTGNW-UHFFFAOYSA-N
Compound NameZ-160
Canonical SMILESO=C(CC(c1ccccc1)c1ccccc1)N1CCN(C(c2ccccc2)c2ccccc2)CC1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)3
Pfam Stratification Cross-Family
Avg pChEMBL6.96
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB12743
Drug NameZ-160
CAS Number41332-24-5
Groups investigational
ATC Codes nan
DescriptionZ160 has been used in trials studying the treatment of Postherpetic Neuralgia and Lumbosacral Radiculopathy.

Categories: Antiarrhythmic agents Benzene Derivatives Calcium Channel Blockers Calcium-Regulating Hormones and Agents Cardiovascular Agents Membrane Transport Modulators
Cross-references: BindingDB: 50461289 CHEMBL604710 ChemSpider: 4168662 PubChem:4988454 PubChem:347828933 ZINC: ZINC000020509316
Target Activities (3)
Target Gene Organism Category Pfam pChEMBL Type Source
P54289 CACNA2D1 Homo sapiens Human PF08473 PF00092 PF08399 7.0 IC50 ChEMBL
Q00975 CACNA1B Homo sapiens Human PF08763 PF16905 PF00520 7.0 IC50 ChEMBL
Q02641 CACNB1 Homo sapiens Human PF00625 PF12052 7.0 IC50 ChEMBL;BindingDB
DrugBank Target Actions (1)
Target Gene Target Name Action Type
P54289 CACNA2D1 Voltage-dependent calcium channel subunit alpha-2/delta-1 inhibitor targets