Molecule Details
| InChIKey | VCPLNXWOFQOPTD-UHFFFAOYSA-N |
|---|---|
| Compound Name | 3-hydroxy-5-methyl-1H-thieno[2,3-d]pyrimidine-2,4-dione |
| Canonical SMILES | Cc1csc2[nH]c(=O)n(O)c(=O)c12 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 3 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 9.23 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (3)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P39748 | FEN1 | Homo sapiens | Human | PF00867 PF00752 | 10.8 | IC50 | ChEMBL;BindingDB |
| P28715 | ERCC5 | Homo sapiens | Human | PF00867 PF00752 | 9.8 | IC50 | ChEMBL;BindingDB |
| Q72547 | pol | Human immunodeficiency virus type 1 | Pathogen | PF00075 PF00078 PF06815 PF06817 | 7.0 | IC50 | ChEMBL;BindingDB |