1-(4-((2-((2,2-Difluorobenzo[d][1,3]dioxol-5-yl)carbamoyl)phenylamino)methyl)pyridin-2-yl)-3-methylurea

InChIKey	`VBXKSTHBDBMAQV-UHFFFAOYSA-N`
Compound Name	1-(4-((2-((2,2-Difluorobenzo[d][1,3]dioxol-5-yl)carbamoyl)phenylamino)methyl)pyridin-2-yl)-3-methylurea
Canonical SMILES	`CNC(=O)Nc1cc(CNc2ccccc2C(=O)Nc2ccc3c(c2)OC(F)(F)O3)ccn1`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	2
Pfam Stratification	Homologous
Avg pChEMBL	8.3
Source	ChEMBL;BindingDB;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P10721	KIT	Homo sapiens	Human	PF00047 PF07714	8.3	IC50	ChEMBL;BindingDB
P15056	BRAF	Homo sapiens	Human	PF00130 PF07714 PF02196	8.3	pIC50	TTD_MultiTarget