N-{4-[(3,4-dichloro-6-fluorophenyl)amino]quinazoline-6-yl}-2-chloroacetamide

InChIKey	`VBXDUSMRNQVJRO-UHFFFAOYSA-N`
Compound Name	N-{4-[(3,4-dichloro-6-fluorophenyl)amino]quinazoline-6-yl}-2-chloroacetamide
Canonical SMILES	`O=C(CCl)Nc1ccc2ncnc(Nc3cc(Cl)c(Cl)cc3F)c2c1`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	2
Pfam Stratification	Homologous
Avg pChEMBL	8.93
Source	ChEMBL;BindingDB;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P04626	ERBB2	Homo sapiens	Human	PF00757 PF14843 PF07714 PF01030 PF21314	10.2	pIC50	TTD_MultiTarget
P00533	EGFR	Homo sapiens	Human	PF00757 PF14843 PF07714 PF01030 PF21314	7.7	IC50	ChEMBL;BindingDB