Molecule Details
InChIKeyVBUWAJWPXASNGM-UHFFFAOYSA-N
Compound Name5-Amino-3-methylsulfanyl-1-pyridin-2-ylpyrazole-4-carboxamide
Canonical SMILESCSc1nn(-c2ccccn2)c(N)c1C(N)=O
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)9
Pfam Stratification Cross-Family
Avg pChEMBL6.11
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (9)
Target Gene Organism Category Pfam pChEMBL Type Source
Q9HAZ1 CLK4 Homo sapiens Human PF00069 6.5 Ki ChEMBL
P08922 ROS1 Homo sapiens Human PF00041 PF07714 6.2 Ki ChEMBL
Q13627 DYRK1A Homo sapiens Human PF00069 6.2 Ki ChEMBL
P48730 CSNK1D Homo sapiens Human PF00069 6.1 Ki ChEMBL
O00444 PLK4 Homo sapiens Human PF00069 PF18190 PF18409 6.0 Ki ChEMBL
P23443 RPS6KB1 Homo sapiens Human PF00069 PF00433 6.0 Ki ChEMBL
P36888 FLT3 Homo sapiens Human PF00047 PF07714 6.0 Ki ChEMBL
Q13555 CAMK2G Homo sapiens Human PF08332 PF00069 6.0 Ki ChEMBL
Q8NE63 HIPK4 Homo sapiens Human PF00069 6.0 Ki ChEMBL