Molecule Details
| InChIKey | UZICFNNDQYSEFG-ICUGJSFKSA-N |
|---|---|
| Compound Name | 1-(4-sulfamoylphenyl)-3-[4-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]selanylphenyl]thiourea |
| Canonical SMILES | NS(=O)(=O)c1ccc(NC(=S)Nc2ccc([Se][C@@H]3O[C@H](CO)[C@H](O)[C@H](O)[C@H]3O)cc2)cc1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 7 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.62 |
| Source | ChEMBL |
2D Structure
Activity Profile
Target Activities (7)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P43166 | CA7 | Homo sapiens | Human | PF00194 | 8.4 | Ki | ChEMBL |
| P00918 | CA2 | Homo sapiens | Human | PF00194 | 8.3 | Ki | ChEMBL |
| Q9Y2D0 | CA5B | Homo sapiens | Human | PF00194 | 8.1 | Ki | ChEMBL |
| O43570 | CA12 | Homo sapiens | Human | PF00194 | 7.7 | Ki | ChEMBL |
| P00915 | CA1 | Homo sapiens | Human | PF00194 | 7.2 | Ki | ChEMBL |
| P35218 | CA5A | Homo sapiens | Human | PF00194 | 7.2 | Ki | ChEMBL |
| P22748 | CA4 | Homo sapiens | Human | PF00194 | 6.5 | Ki | ChEMBL |