[(1S,3R,7S,8S,8aR)-8-[2-[(2R,4R)-4-[tert-butyl(dimethyl)silyl]oxy-6-oxooxan-2-yl]ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] N-[[4-[1-[7-(hydroxyamino)-7-oxoheptyl]triazol-4-yl]phenyl]methyl]carbamate

InChIKey	`UYGBNWBNXHNKCQ-JKZGQAOVSA-N`
Compound Name	[(1S,3R,7S,8S,8aR)-8-[2-[(2R,4R)-4-[tert-butyl(dimethyl)silyl]oxy-6-oxooxan-2-yl]ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] N-[[4-[1-[7-(hydroxyamino)-7-oxoheptyl]triazol-4-yl]phenyl]methyl]carbamate
Canonical SMILES	`C[C@H]1C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O[Si](C)(C)C(C)(C)C)CC(=O)O3)[C@H]2[C@@H](OC(=O)NCc2ccc(-c3cn(CCCCCCC(=O)NO)nn3)cc2)C1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	4
Pfam Stratification	Cross-Family
Avg pChEMBL	6.92
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
Q9UBN7	HDAC6	Homo sapiens	Human	PF00850 PF02148	7.5	IC50	ChEMBL;BindingDB
P04035	HMGCR	Homo sapiens	Human	PF00368 PF12349	7.3	IC50	ChEMBL;BindingDB
Q13547	HDAC1	Homo sapiens	Human	PF00850	6.9	IC50	ChEMBL;BindingDB
Q92769	HDAC2	Homo sapiens	Human	PF00850	6.0	IC50	ChEMBL;BindingDB