Molecule Details
InChIKeyUXLHUPGETZEDBZ-NVMPUMLXSA-N
Compound Nameethyl (2Z)-7-methyl-3-oxo-5-phenyl-2-[[1-[(4-phenylphenyl)methyl]indol-3-yl]methylidene]-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate
Canonical SMILESCCOC(=O)C1=C(C)N=c2s/c(=C\c3cn(Cc4ccc(-c5ccccc5)cc4)c4ccccc34)c(=O)n2C1c1ccccc1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)3
Pfam Stratification Homologous
Avg pChEMBL6.92
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (3)
Target Gene Organism Category Pfam pChEMBL Type Source
Q07817 BCL2L1 Homo sapiens Human PF00452 PF02180 7.8 Ki ChEMBL
Q07820 MCL1 Homo sapiens Human PF00452 6.7 Ki ChEMBL;BindingDB
P10415 BCL2 Homo sapiens Human PF00452 PF02180 6.3 Ki ChEMBL