4,4,4-trifluoro-N-(3-fluoro-4-(2-(1-methyl-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yloxy)phenyl)-3-(phenylamino)butanamide

InChIKey	`UXBXTSWBNHTFRX-UHFFFAOYSA-N`
Compound Name	4,4,4-trifluoro-N-(3-fluoro-4-(2-(1-methyl-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yloxy)phenyl)-3-(phenylamino)butanamide
Canonical SMILES	`Cn1cnc(-c2cc3nccc(Oc4ccc(NC(=O)CC(Nc5ccccc5)C(F)(F)F)cc4F)c3s2)c1`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	3
Pfam Stratification	Homologous
Avg pChEMBL	6.58
Source	ChEMBL;BindingDB;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P08581	MET	Homo sapiens	Human	PF07714 PF01437 PF01403 PF01833	6.7	pIC50	TTD_MultiTarget
P35968	KDR	Homo sapiens	Human	PF07679 PF00047 PF13895 PF22971 PF07714 PF21339 PF17988 PF22854	6.7	IC50	ChEMBL;BindingDB
Q04912	MST1R	Homo sapiens	Human	PF07714 PF01437 PF01403 PF01833	6.4	IC50	ChEMBL;BindingDB