Molecule Details
| InChIKey | UWFYSQMTEOIJJG-FDTZYFLXSA-N |
|---|---|
| Compound Name | Cyproterone Acetate |
| Canonical SMILES | CC(=O)O[C@]1(C(C)=O)CC[C@H]2[C@@H]3C=C(Cl)C4=CC(=O)[C@@H]5C[C@@H]5[C@]4(C)[C@H]3CC[C@@]21C |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 3 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 6.87 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
DrugBank Annotations
| DrugBank ID | DB04839 |
|---|---|
| Drug Name | Cyproterone acetate |
| CAS Number | 427-51-0 |
| Groups | approved investigational |
| ATC Codes | G03HB01 G03HA01 |
| Description | An anti-androgen that, in the form of its acetate (cyproterone acetate), also has progestational properties. It is used in the treatment of hypersexuality in males, as a palliative in prostatic carcinoma, and, in combination with estrogen, for the therapy of severe acne and hirsutism in females. |
Categories: Adrenal Cortex Hormones Antiandrogens Antiandrogens and Estrogens Antineoplastic Agents Combination Contraceptives (with Estrogen and derivatives) Contraceptive Agents, Female Contraceptive Agents, Male Contraceptives, Oral Cytochrome P-450 CYP3A Inhibitors Cytochrome P-450 CYP3A Substrates Cytochrome P-450 CYP3A4 Inhibitors Cytochrome P-450 CYP3A4 Inhibitors (weak) Cytochrome P-450 CYP3A4 Substrates Cytochrome P-450 Enzyme Inhibitors Cytochrome P-450 Substrates Fused-Ring Compounds Genito Urinary System and Sex Hormones Hormonal Contraceptives for Systemic Use Hormone Antagonists Hormones, Hormone Substitutes, and Hormone Antagonists Hyperglycemia-Associated Agents Other Miscellaneous Therapeutic Agents Pregnadienes Pregnanes Progestin Contraceptives Progestins Reproductive Control Agents Sex Hormones and Modulators of the Genital System Steroids Steroids, Chlorinated
Cross-references: BindingDB: 50094569 ChEBI: 50743 CHEMBL139835 ChemSpider: 9496 Drugs Product Database (DPD): 7572 D01368 PDB: CA4 PharmGKB: PA10049 PubChem:9880 PubChem:46506931 RxCUI: 22054 Therapeutic Targets Database: DAP000906 Wikipedia: Cyproterone_acetate ZINC: ZINC000003814423