Molecule Details
InChIKeyUVZVWLFSZNPMBS-UHFFFAOYSA-N
Compound NameN2-(2-(methylthio)benzyl)-N4-((4-(aminomethyl)cyclohexyl)methyl)-5-nitropyrimidine-2,4-diamine
Canonical SMILESCSc1ccccc1CNc1ncc([N+](=O)[O-])c(NCC2CCC(CN)CC2)n1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)17
Pfam Stratification Homologous
Avg pChEMBL6.58
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (17)
Target Gene Organism Category Pfam pChEMBL Type Source
Q04759 PRKCQ Homo sapiens Human PF00130 PF21494 PF00069 PF00433 8.3 IC50 ChEMBL;BindingDB
Q05655 PRKCD Homo sapiens Human PF00130 PF21494 PF00069 PF00433 7.7 Ki ChEMBL
Q13188 STK3 Homo sapiens Human PF11629 PF00069 6.9 Ki ChEMBL
P51812 RPS6KA3 Homo sapiens Human PF00069 PF00433 6.7 Ki ChEMBL
P06493 CDK1 Homo sapiens Human PF00069 6.6 Ki ChEMBL
Q9Y4K4 MAP4K5 Homo sapiens Human PF00780 PF00069 6.6 Ki ChEMBL
O95819 MAP4K4 Homo sapiens Human PF00780 PF00069 6.5 Ki ChEMBL
P24941 CDK2 Homo sapiens Human PF00069 6.5 Ki ChEMBL
P53350 PLK1 Homo sapiens Human PF00069 PF00659 6.4 Ki ChEMBL
O94806 PRKD3 Homo sapiens Human PF00130 PF00169 PF00069 PF25525 6.3 Ki ChEMBL
Q13131 PRKAA1 Homo sapiens Human PF16579 PF21147 PF00069 6.3 Ki ChEMBL
Q9H2G2 SLK Homo sapiens Human PF00069 PF12474 6.3 Ki ChEMBL
Q13555 CAMK2G Homo sapiens Human PF08332 PF00069 6.2 Ki ChEMBL
Q9BXA7 TSSK1B Homo sapiens Human PF00069 6.2 Ki ChEMBL
Q9HCP0 CSNK1G1 Homo sapiens Human PF12605 PF00069 6.2 Ki ChEMBL
Q13557 CAMK2D Homo sapiens Human PF08332 PF00069 6.1 Ki ChEMBL
P51617 IRAK1 Homo sapiens Human PF00531 PF00069 6.0 Ki ChEMBL