Molecule Details
InChIKeyUVSWWUWQVAQPJR-UHFFFAOYSA-N
Compound NameCutamesine
Canonical SMILESCOc1ccc(CCN2CCN(CCCc3ccccc3)CC2)cc1OC
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)3
Pfam Stratification Cross-Family
Avg pChEMBL8.11
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB06618
Drug NameCutamesine
CAS Number165377-43-5
Groups investigational
ATC Codes nan
Descriptionnan
Categories: Central Nervous System Agents Nootropic Agents Receptors, sigma, agonists
Cross-references: BindingDB: 50338990 CHEMBL408867 ChemSpider: 8082975 Wikipedia: Cutamesine ZINC: ZINC000022012325
Target Activities (3)
Target Gene Organism Category Pfam pChEMBL Type Source
Q15125 EBP Homo sapiens Human PF05241 8.8 Ki ChEMBL;BindingDB
Q99720 SIGMAR1 Homo sapiens Human PF04622 8.4 Ki ChEMBL;BindingDB
Q5BJF2 TMEM97 Homo sapiens Human PF05241 7.2 Ki ChEMBL
DrugBank Target Actions (1)
Target Gene Target Name Action Type
Q99720 SIGMAR1 Sigma non-opioid intracellular receptor 1 agonist targets