Molecule Details
| InChIKey | UVERBUNNCOKGNZ-CQSZACIVSA-N |
|---|---|
| Compound Name | Grl-0617 |
| Canonical SMILES | Cc1ccc(N)cc1C(=O)N[C@H](C)c1cccc2ccccc12 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 2 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 6.22 |
| Source | BindingDB;ChEMBL |
2D Structure
Activity Profile
DrugBank Annotations
| DrugBank ID | DB08656 |
|---|---|
| Drug Name | 5-amino-2-methyl-N-[(1R)-1-naphthalen-1-ylethyl]benzamide |
| CAS Number | nan |
| Groups | experimental |
| ATC Codes | nan |
| Description | nan |
Cross-references: BindingDB: 31524 CHEMBL549695 ChemSpider: 24617535 PDB: TTT PubChem:24941262 PubChem:99445127 ZINC: ZINC000043012570
Target Activities (2)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P0C6U8 | Severe acute respiratory syndrome coronavirus | Pathogen | PF16251 PF11501 PF12379 PF12124 PF11633 PF09401 PF19211 PF19218 PF16348 PF19217 PF19213 PF08716 PF08717 PF08710 PF08715 PF01661 PF05409 | 6.2 | IC50 | BindingDB | |
| P0C6X7 | rep | Severe acute respiratory syndrome coronavirus | Pathogen | PF13087 PF16251 PF11501 PF12379 PF12124 PF11633 PF06471 PF06460 PF09401 PF20631 PF20633 PF20632 PF19215 PF19216 PF19219 PF19211 PF19218 PF16348 PF19217 PF19213 PF08716 PF08717 PF08710 PF08715 PF06478 PF01661 PF05409 PF00680 | 6.2 | IC50 | ChEMBL;BindingDB |
DrugBank Target Actions (1)
| Target | Gene | Target Name | Action | Type |
|---|---|---|---|---|
| P0C6X7 | rep | Replicase polyprotein 1ab | binder | targets |