US9687479, 22 N-[(5-chlorothiophen-2-yl)methyl]-1-[(2-methoxyphenyl)carbonyl]-3-(pyridin-2-yl)-1H-1,2,4-triazol-5-amine

InChIKey	`UVDLZNNZPDZTET-UHFFFAOYSA-N`
Compound Name	US9687479, 22 N-[(5-chlorothiophen-2-yl)methyl]-1-[(2-methoxyphenyl)carbonyl]-3-(pyridin-2-yl)-1H-1,2,4-triazol-5-amine
Canonical SMILES	`COc1ccccc1C(=O)n1nc(-c2ccccn2)nc1NCc1ccc(Cl)s1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Homologous
Avg pChEMBL	7.42
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P00734	F2	Homo sapiens	Human	PF00594 PF00051 PF09396 PF00089	9.0	IC50	ChEMBL
P00742	F10	Homo sapiens	Human	PF00008 PF14670 PF00594 PF00089	7.0	IC50	ChEMBL
P03952	KLKB1	Homo sapiens	Human	PF00024 PF00089	6.3	IC50	ChEMBL;BindingDB