Molecule Details
InChIKeyUVANEUUATLLBKA-UHFFFAOYSA-N
Compound Name14,19-Dioxa-5,7,27-triazatetracyclo[19.3.1.12,6.18,12]heptacosa-1(24),2(27),3,5,8(26),9,11,16,21(25),22-decaen-11-ol
Canonical SMILESOc1ccc2cc1COCC=CCOCc1cccc(c1)-c1ccnc(n1)N2
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)7
Pfam Stratification Cross-Family
Avg pChEMBL6.75
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (7)
Target Gene Organism Category Pfam pChEMBL Type Source
O60674 JAK2 Homo sapiens Human PF18379 PF18377 PF17887 PF07714 PF21990 7.3 IC50 ChEMBL;BindingDB
P29597 TYK2 Homo sapiens Human PF18379 PF18377 PF17887 PF07714 PF21990 6.8 IC50 ChEMBL;BindingDB
P36888 FLT3 Homo sapiens Human PF00047 PF07714 6.8 IC50 ChEMBL;BindingDB
P20248 CCNA2 Homo sapiens Human PF02984 PF00134 PF16500 6.7 IC50 ChEMBL
P24941 CDK2 Homo sapiens Human PF00069 6.7 IC50 ChEMBL
P78396 CCNA1 Homo sapiens Human PF02984 PF00134 PF16500 6.7 IC50 ChEMBL
P23458 JAK1 Homo sapiens Human PF18379 PF18377 PF17887 PF07714 PF21990 6.4 IC50 ChEMBL;BindingDB