Molecule Details
| InChIKey | UUXJPDYOJAJQGO-UHFFFAOYSA-N |
|---|---|
| Compound Name | N-{6-cyano-1-[(1-methyl-1H-imidazol-5-yl)methyl]-1,2,3,4-tetrahydroquinolin-3-yl}-N-[(5-methyl-3-phenyl-1,2-oxazol-4-yl)methyl]pyridine-2-sulfonamide |
| Canonical SMILES | Cc1onc(-c2ccccc2)c1CN(C1Cc2cc(C#N)ccc2N(Cc2cncn2C)C1)S(=O)(=O)c1ccccn1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 8.81 |
| Source | BindingDB;ChEMBL |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P49354 | FNTA | Homo sapiens | Human | PF01239 | 8.5 | IC50 | ChEMBL;BindingDB |
| P49356 | FNTB | Homo sapiens | Human | PF00432 | 8.5 | IC50 | ChEMBL |
| Q5E175 | rhlE | Aliivibrio fischeri (strain ATCC 700601 / ES114) | Pathogen | PF00270 PF00271 | 9.1 | IC50 | BindingDB |
| Q5EI73 | Plasmodium falciparum | Pathogen | PF01239 | 9.1 | IC50 | ChEMBL |