Molecule Details
| InChIKey | UUDAMDVQRQNNHZ-YFKPBYRVSA-N |
|---|---|
| Compound Name | (S)-Ampa |
| Canonical SMILES | Cc1onc(O)c1C[C@H](N)C(=O)O |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.37 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
DrugBank Annotations
| DrugBank ID | DB02057 |
|---|---|
| Drug Name | (S)-AMPA |
| CAS Number | 83643-88-3 |
| Groups | experimental |
| ATC Codes | nan |
| Description | AMPA is a specific agonist for the AMPA receptor. |
Cross-references: BindingDB: 85214 CHEMBL276815 ChemSpider: 139348 PDB: AMQ PubChem:158397 PubChem:46505942 Wikipedia: AMPA ZINC: ZINC000002047472
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P42263 | GRIA3 | Homo sapiens | Human | PF01094 PF00060 PF10613 | 7.7 | Ki | ChEMBL;BindingDB |
| P42262 | GRIA2 | Homo sapiens | Human | PF01094 PF00060 PF10613 | 7.4 | Ki | ChEMBL;BindingDB |
| P42261 | GRIA1 | Homo sapiens | Human | PF01094 PF00060 PF10613 | 7.3 | Ki | ChEMBL;BindingDB |
| P48058 | GRIA4 | Homo sapiens | Human | PF01094 PF00060 PF10613 | 7.1 | Ki | ChEMBL;BindingDB |