Molecule Details
| InChIKey | UUDAMDVQRQNNHZ-UHFFFAOYSA-N |
|---|---|
| Compound Name | alpha-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID |
| Canonical SMILES | Cc1onc(O)c1CC(N)C(=O)O |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 5 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.31 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (5)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P42262 | GRIA2 | Homo sapiens | Human | PF01094 PF00060 PF10613 | 7.7 | IC50 | ChEMBL;BindingDB |
| P42263 | GRIA3 | Homo sapiens | Human | PF01094 PF00060 PF10613 | 7.7 | IC50 | ChEMBL;BindingDB |
| P42261 | GRIA1 | Homo sapiens | Human | PF01094 PF00060 PF10613 | 7.7 | IC50 | ChEMBL;BindingDB |
| P48058 | GRIA4 | Homo sapiens | Human | PF01094 PF00060 PF10613 | 7.4 | IC50 | ChEMBL;BindingDB |
| P39086 | GRIK1 | Homo sapiens | Human | PF01094 PF00060 PF10613 | 6.1 | Ki | ChEMBL;BindingDB |