UTPDQPQSXIPZQG-CYBMUJFWSA-N

InChIKey	`UTPDQPQSXIPZQG-CYBMUJFWSA-N`
Canonical SMILES	`COc1cccc([C@@H](C)NC(=O)c2ccc(-c3c[nH]nc3C#N)cc2OC)c1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	2
Pfam Stratification	Homologous
Avg pChEMBL	7.59
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
O75116	ROCK2	Homo sapiens	Human	PF25346 PF00069 PF08912	7.7	IC50	ChEMBL;BindingDB
Q13464	ROCK1	Homo sapiens	Human	PF25346 PF00069 PF08912	7.5	IC50	ChEMBL;BindingDB