2,4-Dipyrrolidin-1-yl-6-[4-[[4-(trifluoromethyl)phenyl]methyl]piperazin-1-yl]pyrimidine

InChIKey	`UTNIELHSQXTLFN-UHFFFAOYSA-N`
Compound Name	2,4-Dipyrrolidin-1-yl-6-[4-[[4-(trifluoromethyl)phenyl]methyl]piperazin-1-yl]pyrimidine
Canonical SMILES	`FC(F)(F)c1ccc(CN2CCN(c3cc(N4CCCC4)nc(N4CCCC4)n3)CC2)cc1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Homologous
Avg pChEMBL	6.42
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P51878	CASP5	Homo sapiens	Human	PF00619 PF00656	6.5	IC50	ChEMBL;BindingDB
P29466	CASP1	Homo sapiens	Human	PF00619 PF00656	6.5	IC50	ChEMBL;BindingDB
P49662	CASP4	Homo sapiens	Human	PF00619 PF00656	6.2	Ki	ChEMBL;BindingDB