Molecule Details
InChIKeyUTMRCMCLMBDPNW-UHFFFAOYSA-N
Compound Name3-[[4-[8-(2-Aminoethyl)-2-(4-fluorophenyl)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-2-yl]amino]-2,2-dimethylpropan-1-ol
Canonical SMILESCC(C)(CO)CNc1nccc(-c2c(-c3ccc(F)cc3)nc3c(CCN)nccn23)n1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)10
Pfam Stratification Cross-Family
Avg pChEMBL6.52
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (10)
Target Gene Organism Category Pfam pChEMBL Type Source
P48730 CSNK1D Homo sapiens Human PF00069 8.1 Ki ChEMBL
P45984 MAPK9 Homo sapiens Human PF00069 6.7 Ki ChEMBL
P48729 CSNK1A1 Homo sapiens Human PF00069 6.7 Ki ChEMBL
P17948 FLT1 Homo sapiens Human PF07679 PF00047 PF13927 PF22971 PF07714 PF21339 PF17988 PF22854 6.5 Ki ChEMBL
P36888 FLT3 Homo sapiens Human PF00047 PF07714 6.5 Ki ChEMBL
Q9Y4K4 MAP4K5 Homo sapiens Human PF00780 PF00069 6.4 Ki ChEMBL
O94806 PRKD3 Homo sapiens Human PF00130 PF00169 PF00069 PF25525 6.1 Ki ChEMBL
P78368 CSNK1G2 Homo sapiens Human PF12605 PF00069 6.1 Ki ChEMBL
Q9HCP0 CSNK1G1 Homo sapiens Human PF12605 PF00069 6.1 Ki ChEMBL
Q96GD4 AURKB Homo sapiens Human PF00069 6.0 Ki ChEMBL