Molecule Details
InChIKeyUSVCWSAJUAARAL-MEMLXQNLSA-N
Canonical SMILESNc1ncnc2c1c(-c1cccc(OCc3ccccc3)c1)cn2[C@H]1C[C@H](N2CCC2)C1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)8
Pfam Stratification Cross-Family
Avg pChEMBL6.88
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (8)
Target Gene Organism Category Pfam pChEMBL Type Source
Q13535 ATR Homo sapiens Human PF02259 PF02260 PF23593 PF25030 PF25032 PF00454 PF08064 8.3 Kd ChEMBL
Q6P5Z2 PKN3 Homo sapiens Human PF02185 PF00069 PF00433 7.6 Kd ChEMBL
P08069 IGF1R Homo sapiens Human PF00757 PF07714 PF01030 7.1 IC50 ChEMBL;BindingDB
Q13163 MAP2K5 Homo sapiens Human PF00564 PF00069 6.8 Kd ChEMBL
P07947 YES1 Homo sapiens Human PF07714 PF00017 PF00018 6.5 Kd ChEMBL
O43353 RIPK2 Homo sapiens Human PF00619 PF07714 6.5 Kd ChEMBL
P08631 HCK Homo sapiens Human PF07714 PF00017 PF00018 6.2 Kd ChEMBL
Q8NI60 COQ8A Homo sapiens Human PF03109 6.1 Kd ChEMBL