Molecule Details
InChIKeyUSHMNZBDAOGLMB-UHFFFAOYSA-N
Compound Name1-[3,5-bis[N-(diaminomethylideneamino)-C-methylcarbonimidoyl]phenyl]-3-[6-[[3,5-bis[N-(diaminomethylideneamino)-C-methylcarbonimidoyl]phenyl]carbamoylamino]hexyl]urea
Canonical SMILESCC(=NNC(=N)N)c1cc(NC(=O)NCCCCCCNC(=O)Nc2cc(C(C)=NNC(=N)N)cc(C(C)=NNC(=N)N)c2)cc(C(C)=NNC(=N)N)c1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)26
Pfam Stratification Cross-Family
Avg pChEMBL6.33
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (26)
Target Gene Organism Category Pfam pChEMBL Type Source
O43293 DAPK3 Homo sapiens Human PF00069 6.8 Ki ChEMBL
P11309 PIM1 Homo sapiens Human PF00069 6.8 Ki ChEMBL
Q9P1W9 PIM2 Homo sapiens Human PF00069 6.7 Ki ChEMBL
P23443 RPS6KB1 Homo sapiens Human PF00069 PF00433 6.5 Ki ChEMBL
P51812 RPS6KA3 Homo sapiens Human PF00069 PF00433 6.5 Ki ChEMBL
Q05655 PRKCD Homo sapiens Human PF00130 PF21494 PF00069 PF00433 6.5 Ki ChEMBL
Q5VT25 CDC42BPA Homo sapiens Human PF00130 PF00780 PF08826 PF15796 PF25346 PF00069 PF00433 6.5 Ki ChEMBL
P31749 AKT1 Homo sapiens Human PF00169 PF00069 PF00433 6.4 Ki ChEMBL
Q05513 PRKCZ Homo sapiens Human PF00130 PF00564 PF00069 PF00433 6.4 Ki ChEMBL
Q13153 PAK1 Homo sapiens Human PF00786 PF00069 6.4 Ki ChEMBL
Q9Y243 AKT3 Homo sapiens Human PF00169 PF00069 PF00433 6.4 Ki ChEMBL
O15111 CHUK Homo sapiens Human PF18397 PF12179 PF00069 6.3 Ki ChEMBL
P24941 CDK2 Homo sapiens Human PF00069 6.3 Ki ChEMBL
Q13188 STK3 Homo sapiens Human PF11629 PF00069 6.3 Ki ChEMBL
Q13464 ROCK1 Homo sapiens Human PF25346 PF00069 PF08912 6.3 Ki ChEMBL
P05129 PRKCG Homo sapiens Human PF00130 PF00168 PF00069 PF00433 6.2 Ki ChEMBL
P06493 CDK1 Homo sapiens Human PF00069 6.2 Ki ChEMBL
P49137 MAPKAPK2 Homo sapiens Human PF00069 6.2 Ki ChEMBL
Q16644 MAPKAPK3 Homo sapiens Human PF00069 6.2 Ki ChEMBL
Q9BZL6 PRKD2 Homo sapiens Human PF00130 PF00169 PF00069 PF25525 6.2 Ki ChEMBL
O14757 CHEK1 Homo sapiens Human PF00069 6.1 Ki ChEMBL
O75116 ROCK2 Homo sapiens Human PF25346 PF00069 PF08912 6.1 Ki ChEMBL
O96017 CHEK2 Homo sapiens Human PF00498 PF00069 6.1 Ki ChEMBL
P31751 AKT2 Homo sapiens Human PF00169 PF00069 PF00433 6.1 Ki ChEMBL
O60674 JAK2 Homo sapiens Human PF18379 PF18377 PF17887 PF07714 PF21990 6.0 Ki ChEMBL
P52333 JAK3 Homo sapiens Human PF18379 PF18377 PF17887 PF07714 PF21990 6.0 Ki ChEMBL