Molecule Details
InChIKeyURCVCIZFVQDVPM-UHFFFAOYSA-N
Compound NameN-(2-((4-hydroxyphenyl)amino)-3-pyridinyl)-4-methoxybenzenesulfonamide
Canonical SMILESCOc1ccc(S(=O)(=O)Nc2cccnc2Nc2ccc(O)cc2)cc1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)15
Pfam Stratification Homologous
Avg pChEMBL6.16
SourceChEMBL
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB12254
Drug NameABT-751
CAS Number141430-65-1
Groups investigational
ATC Codes nan
DescriptionABT-751 has been investigated for the treatment of Lung Cancer, Non-Small Cell Lung Cancer, and Non-Small-Cell Lung Cancer.

Categories: Amides Amines Aniline Compounds Benzene Derivatives Phenols Sulfonamides Sulfones Sulfur Compounds
Cross-references: BindingDB: 50101086 ChEBI: 95043 CHEMBL20684 ChemSpider: 2299887 PDB: E70 PubChem:3035714 PubChem:347828529 ZINC: ZINC000000598089
Target Activities (15)
Target Gene Organism Category Pfam pChEMBL Type Source
P04350 TUBB4A Homo sapiens Human PF00091 PF03953 6.2 IC50 ChEMBL
P07437 TUBB Homo sapiens Human PF00091 PF03953 6.2 IC50 ChEMBL
P0DPH7 TUBA3C Homo sapiens Human PF00091 PF03953 6.2 IC50 ChEMBL
P68363 TUBA1B Homo sapiens Human PF00091 PF03953 6.2 IC50 ChEMBL
P68366 TUBA4A Homo sapiens Human PF00091 PF03953 6.2 IC50 ChEMBL
P68371 TUBB4B Homo sapiens Human PF00091 PF03953 6.2 IC50 ChEMBL
Q13509 TUBB3 Homo sapiens Human PF00091 PF03953 6.2 IC50 ChEMBL
Q13885 TUBB2A Homo sapiens Human PF00091 PF03953 6.2 IC50 ChEMBL
Q3ZCM7 TUBB8 Homo sapiens Human PF00091 PF03953 6.2 IC50 ChEMBL
Q6PEY2 TUBA3E Homo sapiens Human PF00091 PF03953 6.2 IC50 ChEMBL
Q71U36 TUBA1A Homo sapiens Human PF00091 PF03953 6.2 IC50 ChEMBL
Q9BQE3 TUBA1C Homo sapiens Human PF00091 PF03953 6.2 IC50 ChEMBL
Q9BUF5 TUBB6 Homo sapiens Human PF00091 PF03953 6.2 IC50 ChEMBL
Q9BVA1 TUBB2B Homo sapiens Human PF00091 PF03953 6.2 IC50 ChEMBL
Q9H4B7 TUBB1 Homo sapiens Human PF00091 PF03953 6.2 IC50 ChEMBL