Molecule Details
| InChIKey | UQPBEYBGEYZEHF-UHFFFAOYSA-N |
|---|---|
| Compound Name | N-[(6-chloro-2,1,3-benzothiadiazol-5-yl)methyl]-N-{6-cyano-1-[(1-methyl-1H-imidazol-5-yl)methyl]-1,2,3,4-tetrahydroquinolin-3-yl}pyridine-2-sulfonamide |
| Canonical SMILES | Cn1cncc1CN1CC(N(Cc2cc3nsnc3cc2Cl)S(=O)(=O)c2ccccn2)Cc2cc(C#N)ccc21 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 7.63 |
| Source | BindingDB;ChEMBL |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P49354 | FNTA | Homo sapiens | Human | PF01239 | 8.0 | IC50 | ChEMBL;BindingDB |
| P49356 | FNTB | Homo sapiens | Human | PF00432 | 8.0 | IC50 | ChEMBL |
| Q5E175 | rhlE | Aliivibrio fischeri (strain ATCC 700601 / ES114) | Pathogen | PF00270 PF00271 | 7.3 | IC50 | BindingDB |
| Q5EI73 | Plasmodium falciparum | Pathogen | PF01239 | 7.3 | IC50 | ChEMBL |