Molecule Details
InChIKeyUQAWGIKJINAKIZ-UHFFFAOYSA-N
Compound NamePhenylaminoimidazo(1,2-alpha)pyridine
Canonical SMILESNS(=O)(=O)c1ccc(Nc2cn3cc(C(=O)c4c(Cl)cccc4Cl)ccc3n2)cc1
Clinical Status Clinical Multi-Target
Targets (Human+Pathogen)8
Pfam Stratification Cross-Family
Avg pChEMBL6.34
SourceChEMBL;BindingDB;TTD_MultiTarget
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB04607
Drug NamePHENYLAMINOIMIDAZO(1,2-ALPHA)PYRIDINE
CAS Numbernan
Groups experimental
ATC Codes nan
Descriptionnan

Cross-references: BindingDB: 6670 CHEMBL182260 ChemSpider: 4487759 PDB: 628 PubChem:5330608 PubChem:46506780 ZINC: ZINC000012504436
Target Activities (8)
Target Gene Organism Category Pfam pChEMBL Type Source
O95067 CCNB2 Homo sapiens Human PF02984 PF00134 6.4 IC50 ChEMBL
P06493 CDK1 Homo sapiens Human PF00069 6.4 IC50 ChEMBL;BindingDB
P14635 CCNB1 Homo sapiens Human PF02984 PF00134 6.4 IC50 ChEMBL
Q8WWL7 CCNB3 Homo sapiens Human PF02984 PF00134 6.4 IC50 ChEMBL
P11802 CDK4 Homo sapiens Human PF00069 6.3 pIC50 TTD_MultiTarget
O96020 CCNE2 Homo sapiens Human PF02984 PF00134 6.2 IC50 ChEMBL
P24864 CCNE1 Homo sapiens Human PF02984 PF00134 6.2 IC50 ChEMBL
P24941 CDK2 Homo sapiens Human PF00069 6.2 pIC50 TTD_MultiTarget
DrugBank Target Actions (1)
Target Gene Target Name Action Type
P24941 CDK2 Cyclin-dependent kinase 2 inhibitor targets