Molecule Details
InChIKeyUPPGGRZNGRFDAU-UHFFFAOYSA-N
Compound Name3-benzyl-5-(1H-indazol-5-yl)-N-methyl-N-propan-2-yltriazole-4-carboxamide
Canonical SMILESCC(C)N(C)C(=O)c1c(-c2ccc3[nH]ncc3c2)nnn1Cc1ccccc1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)21
Pfam Stratification Homologous
Avg pChEMBL6.89
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (21)
Target Gene Organism Category Pfam pChEMBL Type Source
P51817 PRKX Homo sapiens Human PF00069 7.9 Ki ChEMBL
P49841 GSK3B Homo sapiens Human PF00069 7.8 Ki ChEMBL
O75116 ROCK2 Homo sapiens Human PF25346 PF00069 PF08912 7.5 Ki ChEMBL
Q5VT25 CDC42BPA Homo sapiens Human PF00130 PF00780 PF08826 PF15796 PF25346 PF00069 PF00433 7.5 Ki ChEMBL
P49840 GSK3A Homo sapiens Human PF00069 7.4 Ki ChEMBL
Q13976 PRKG1 Homo sapiens Human PF00027 PF16808 PF00069 7.1 Ki ChEMBL
O14965 AURKA Homo sapiens Human PF00069 7.0 Ki ChEMBL
P06493 CDK1 Homo sapiens Human PF00069 7.0 Ki ChEMBL
P24941 CDK2 Homo sapiens Human PF00069 7.0 Ki ChEMBL
Q96GD4 AURKB Homo sapiens Human PF00069 6.9 Ki ChEMBL
O75582 RPS6KA5 Homo sapiens Human PF00069 PF00433 6.8 Ki ChEMBL
P23443 RPS6KB1 Homo sapiens Human PF00069 PF00433 6.7 Ki ChEMBL
Q13627 DYRK1A Homo sapiens Human PF00069 6.7 Ki ChEMBL
O00444 PLK4 Homo sapiens Human PF00069 PF18190 PF18409 6.6 Ki ChEMBL
P17612 PRKACA Homo sapiens Human PF00069 6.6 Ki ChEMBL
Q16513 PKN2 Homo sapiens Human PF02185 PF00069 PF00433 6.6 Ki ChEMBL
Q13131 PRKAA1 Homo sapiens Human PF16579 PF21147 PF00069 6.5 Ki ChEMBL
Q13464 ROCK1 Homo sapiens Human PF25346 PF00069 PF08912 6.5 Ki ChEMBL
O00311 CDC7 Homo sapiens Human PF00069 6.3 Ki ChEMBL;BindingDB
Q9HBY8 SGK2 Homo sapiens Human PF00069 PF00433 6.2 Ki ChEMBL
Q9HAZ1 CLK4 Homo sapiens Human PF00069 6.1 Ki ChEMBL