Molecule Details
InChIKeyUPITUWGOTMBQLX-UHFFFAOYSA-N
Canonical SMILESCc1c(C=O)c(O)n2c(nc3ccccc32)c1C#N
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)13
Pfam Stratification Cross-Family
Avg pChEMBL6.4
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (13)
Target Gene Organism Category Pfam pChEMBL Type Source
P68400 CSNK2A1 Homo sapiens Human PF00069 7.2 Ki ChEMBL
P52333 JAK3 Homo sapiens Human PF18379 PF18377 PF17887 PF07714 PF21990 7.0 Ki ChEMBL
P11309 PIM1 Homo sapiens Human PF00069 6.8 Ki ChEMBL
P51451 BLK Homo sapiens Human PF07714 PF00017 PF00018 6.5 Ki ChEMBL
P06241 FYN Homo sapiens Human PF07714 PF00017 PF00018 6.4 Ki ChEMBL
Q08881 ITK Homo sapiens Human PF00779 PF00169 PF07714 PF00017 PF00018 6.4 Ki ChEMBL
Q13627 DYRK1A Homo sapiens Human PF00069 6.3 Ki ChEMBL
P36888 FLT3 Homo sapiens Human PF00047 PF07714 6.2 Ki ChEMBL
O00444 PLK4 Homo sapiens Human PF00069 PF18190 PF18409 6.1 Ki ChEMBL
O14965 AURKA Homo sapiens Human PF00069 6.1 Ki ChEMBL
P35916 FLT4 Homo sapiens Human PF07679 PF13927 PF22971 PF07714 PF21339 PF17988 PF22854 6.1 Ki ChEMBL
Q9H4B4 PLK3 Homo sapiens Human PF00069 PF00659 6.1 Ki ChEMBL
O43293 DAPK3 Homo sapiens Human PF00069 6.0 Ki ChEMBL