Molecule Details
| InChIKey | UPBSKELQKAHWLX-UHFFFAOYSA-N |
|---|---|
| Compound Name | 4-[3-(5-Chloro-2-pyridinyl)-3,8-diazabicyclo[3.2.1]octan-8-yl]-1-(4-fluorophenyl)butan-1-one |
| Canonical SMILES | O=C(CCCN1C2CCC1CN(c1ccc(Cl)cn1)C2)c1ccc(F)cc1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 6 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 6.73 |
| Source | ChEMBL |
2D Structure
Activity Profile
Target Activities (6)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P28223 | HTR2A | Homo sapiens | Human | PF00001 | 7.3 | Ki | ChEMBL |
| P08908 | HTR1A | Homo sapiens | Human | PF00001 | 7.1 | Ki | ChEMBL |
| P21917 | DRD4 | Homo sapiens | Human | PF00001 | 6.9 | Ki | ChEMBL |
| P31645 | SLC6A4 | Homo sapiens | Human | PF03491 PF00209 | 6.6 | Ki | ChEMBL |
| P34969 | HTR7 | Homo sapiens | Human | PF00001 | 6.5 | Ki | ChEMBL |
| P35462 | DRD3 | Homo sapiens | Human | PF00001 | 6.0 | Ki | ChEMBL |