Molecule Details
| InChIKey | UOYIIWVJEPEEOF-UHFFFAOYSA-N |
|---|---|
| Compound Name | 1-[(4-aminocyclohexyl)methyl]-N-methyl-3-(4-phenylphenyl)pyrazolo[3,4-d]pyrimidin-6-amine |
| Canonical SMILES | CNc1ncc2c(-c3ccc(-c4ccccc4)cc3)nn(CC3CCC(N)CC3)c2n1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 3 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.16 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (3)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P30530 | AXL | Homo sapiens | Human | PF00041 PF13927 PF07714 | 7.3 | IC50 | ChEMBL;BindingDB |
| Q12866 | MERTK | Homo sapiens | Human | PF00041 PF00047 PF13927 PF07714 | 7.3 | IC50 | ChEMBL;BindingDB |
| Q06418 | TYRO3 | Homo sapiens | Human | PF00041 PF07679 PF07714 | 6.9 | IC50 | ChEMBL;BindingDB |