Molecule Details
| InChIKey | UORHIBXCPUHXFY-UHFFFAOYSA-N |
|---|---|
| Compound Name | 5-(3-Chlorobenzyl)-3-isopropyl-1,6-dihydro-pyrazolo[4,3-d]pyrimidin-7-one |
| Canonical SMILES | CC(C)c1n[nH]c2c(=O)[nH]c(Cc3cccc(Cl)c3)nc12 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.8 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q14123 | PDE1C | Homo sapiens | Human | PF00233 PF08499 | 8.4 | IC50 | ChEMBL;BindingDB |
| O76083 | PDE9A | Homo sapiens | Human | PF00233 | 8.1 | IC50 | ChEMBL;BindingDB |
| Q01064 | PDE1B | Homo sapiens | Human | PF00233 PF08499 | 7.4 | IC50 | ChEMBL;BindingDB |
| P54750 | PDE1A | Homo sapiens | Human | PF00233 PF08499 | 7.3 | IC50 | ChEMBL;BindingDB |