Molecule Details
| InChIKey | UMKLFWMQTDMELK-SFHVURJKSA-N |
|---|---|
| Compound Name | Carm1-IN-5 |
| Canonical SMILES | CNC[C@H](O)CN(C)Cc1ccccc1OCc1ccc(-c2nccs2)c(Cl)c1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 5 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.15 |
| Source | ChEMBL |
2D Structure
Activity Profile
Target Activities (5)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q86X55 | CARM1 | Homo sapiens | Human | PF11531 PF06325 PF22528 | 8.7 | IC50 | ChEMBL |
| Q96LA8 | PRMT6 | Homo sapiens | Human | PF13649 PF22528 | 7.2 | IC50 | ChEMBL |
| Q9NR22 | PRMT8 | Homo sapiens | Human | PF06325 PF22528 | 7.1 | IC50 | ChEMBL |
| Q99873 | PRMT1 | Homo sapiens | Human | PF13649 PF22528 | 6.7 | IC50 | ChEMBL |
| O60678 | PRMT3 | Homo sapiens | Human | PF21137 PF21336 PF06325 PF22528 | 6.0 | IC50 | ChEMBL |