1-{4-[7-(1H-Indol-5-ylamino)-thieno[3,2-b]pyridin-2-yl]-benzyl}-piperidine-4-carboxylic acid amide

InChIKey	`ULUUNYJTTJIXHY-UHFFFAOYSA-N`
Compound Name	1-{4-[7-(1H-Indol-5-ylamino)-thieno[3,2-b]pyridin-2-yl]-benzyl}-piperidine-4-carboxylic acid amide
Canonical SMILES	`NC(=O)C1CCN(Cc2ccc(-c3cc4nccc(Nc5ccc6[nH]ccc6c5)c4s3)cc2)CC1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	2
Pfam Stratification	Homologous
Avg pChEMBL	8.38
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P00533	EGFR	Homo sapiens	Human	PF00757 PF14843 PF07714 PF01030 PF21314	9.0	IC50	ChEMBL;BindingDB
P17948	FLT1	Homo sapiens	Human	PF07679 PF00047 PF13927 PF22971 PF07714 PF21339 PF17988 PF22854	7.8	IC50	ChEMBL;BindingDB