InChIKey	ULSDMUVEXKOYBU-ZDUSSCGKSA-N
Compound Name	Zolmitriptan
Canonical SMILES	CN(C)CCc1c[nH]c2ccc(C[C@H]3COC(=O)N3)cc12
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Homologous
Avg pChEMBL	8.1
Source	ChEMBL;BindingDB

DrugBank ID	DB00315
Drug Name	Zolmitriptan
CAS Number	139264-17-8
Groups	approved investigational
ATC Codes	N02CC03
Description	Zolmitriptan is a member of the triptan class of 5-hydroxytryptamine(5-HT)<sub>1B/1D/(1F)</sub> receptor agonists used to treat acute migraine.[A462, L12978] [Sumatriptan] was the first triptan to be developed, but had poor oral bioavailability and lipophilicity. This led to the development of secon...

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Categories: Agents that produce hypertension Amines Analgesics Antidepressive Agents Antimigraine Preparations Biogenic Amines Biogenic Monoamines Central Nervous System Depressants Cytochrome P-450 CYP1A2 Substrates Cytochrome P-450 Substrates Heterocyclic Compounds, Fused-Ring Indoles Monoamine Oxidase A Substrates Nervous System Neurotransmitter Agents Oxazoles Selective Serotonin 5-HT1 Receptor Agonists Selective Serotonin Agonists Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome Serotonin 1b Receptor Agonists Serotonin 1d Receptor Agonists Serotonin 5-HT1 Receptor Agonists Serotonin Agents Serotonin Modulators Serotonin Receptor Agonists Serotonin-1b and Serotonin-1d Receptor Agonist Triptans

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Cross-references: BindingDB: 50033383 ChEBI: 10124 CHEMBL1185 ChemSpider: 54844 Drugs Product Database (DPD): 11793 C07218 D00415 PharmGKB: PA451975 PubChem:60857 PubChem:46506452 RxCUI: 135775 Therapeutic Targets Database: DAP000077 Wikipedia: Zolmitriptan ZINC: ZINC000000015515